Urine was analyzed for six metabolites and the method could achieve 90% reliability in distinguishing between bipolar disorder and depression.
A large percentage of BD subjects are incorrectly treated with antidepressants in clinical practice. The consequences can be lethal. Selective seratonin reuptake inhibitors (SSRIs) such as Prozac and Celexa probably don’t help people with bipolar. SSRIs are alleged to increase suicide risk among bipolar patients, a major concern since bipolar sufferers have suicide rates around 20 times the population as a whole.